Average 3. Tested Concept. The primary surgical goal for correction is to obtain fusion in a position that will maintain sitting balance and prevent decline of pulmonary function. Progressive replacement of muscle tissue with fibrous and fatty tissue, causing calf pseudohypertrophy. Abnormal chondroid production by chondroblasts in the proliferative zone of the physis. Disturbances in cell metabolism with accumulation of sphingolipids in the liver, spleen and bone marrow. In addition, the child has absent deep tendon reflexes and hypotonia. Which of the following abnormalities is most likely responsible for these findings? On physical exam, he can sit but cannot walk. He has tongue fasciculations and absent deep tendon reflexes.
Average 4. Duchenne and Becker Muscular Dystrophy. Moises Dominguez. Limb-girdle muscular dystrophy. Please rate topic. Upgrade to PEAK. Sort by. All Videos 1. Login to View Community Videos.
Average 4. They note that he is not able to keep up with his peers in athletic activities. He is unable to climb steps without the aid of a handrail. On exam, he stands with increased lumbar lordosis and a wide based stance. When asked to rise from a seated position on the floor, the child first rolls into a crawling position on all four limbs, stands up by extending his knees and uses his upper extremities bracing against his thighs to help elevate his trunk. You confirm the diagnosis with serum enzyme assay followed by DNA analysis. The parents ask you what the chances are of their child passing on this genetic disease to his male offspring. Tested Concept. On exam, he has has a right thoracic and left lumbar parapinal prominence, pelvic obliquity, and equinovarus foot deformities.
Deficiency of these proteins leads to progressive loss of anterior horn cells and progressive muscle weakness in children. Review more high-yield concepts about this topic on today's episode of the "Orthobullets Audio Review" wherever you listen to podcasts! Jump to. Sections of this page. Accessibility Help. Email or Phone Password Forgot account? Sign Up.