Breast hypertrophy is a rare medical condition of the breast connective tissues in which the breasts become excessively large. The condition is often divided based on the severity into two types, macromastia and gigantomastia. Hypertrophy of the breast tissues may be caused by increased histologic sensitivity to certain hormones such as female sex hormones , prolactin , and growth factors. It was first scientifically described in Some resources distinguish between macromastia Greek, macro : large, mastos : breast , where excessive tissue is less than 2. Hypertrophy of the breast can affect the breasts equally, but usually affects one breast more than the other, thereby causing asymmetry, when one breast is larger than the other. The condition can also individually affect the nipples and areola instead of or in addition to the entire breast.
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Gigantomastia is a rare condition that causes excessive growth of the female breasts. Only a couple hundred cases have been reported in the medical literature. The exact cause of gigantomastia isn't known.
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